Luxury Vacation Rentals for Large Groups in St. Louis

Never book a bad vacation home again. Every Wander comes with hotel-grade amenities, inspiring views, pristine cleaning and 24/7 concierge service.

We found 8 large group vacation rentals – enter your dates for availability.

Top-rated large group vacation rentals in St. Louis

5431 Pernod Avenue

5 bedrooms•2 baths

•

New

~$95 less than other sites

The Chase off Grand: Historic Shaw Home, Near Zoo & Arch

5 bedrooms•2 baths

•

~$40 less than other sites

6121 W Park Ave

4 bedrooms•2.5 baths

•

New

~$80 less than other sites

StayAtlas Retreat w/ Pool, Gym, Games, BBQ

7 bedrooms•6 baths

•

~$95 less than other sites

Lou Luxe- Speakeasy, EPIC Arcade, Hottub & FirePit

5 bedrooms•3 baths

•

~$80 less than other sites

Historic St Louis Retreat, Two Levels

6 bedrooms•4 baths

•

New

~$125 less than other sites

Luxury Living: Grand near Everything

7 bedrooms•5 baths

•

~$75 less than other sites

317 N 4th Street

4 bedrooms•1.5 baths

•

New

~$65 less than other sites

Welcome to your large group retreat in St. Louis

At Wander, luxury large-group vacation rentals in St. Louis combine hotel polish with the comfort of a private home. Expansive living rooms, generous dining zones, and chef-ready kitchens make it easy to gather, dine, and reconnect. Multi-bedroom layouts with several suites and flexible sleeping arrangements keep everyone comfortable.

Every stay delivers hotel-grade amenities, ultra fast WiFi, pristine cleaning, and 24/7 concierge. Expect plush linens, spa-quality baths, and intuitive smart features throughout. Select homes add gyms, pools, media lounges, and ample parking for retreats, reunions, and offsites. Enjoy unwavering quality and beautiful design, so your group can focus on the moments that matter.

Available soon in St. Louis

5431 Pernod Avenue

5 bedrooms•2 baths

•

New

~$95 less than other sites

The Chase off Grand: Historic Shaw Home, Near Zoo & Arch

5 bedrooms•2 baths

•

~$40 less than other sites

StayAtlas Retreat w/ Pool, Gym, Games, BBQ

7 bedrooms•6 baths

•

~$95 less than other sites

Lou Luxe- Speakeasy, EPIC Arcade, Hottub & FirePit

5 bedrooms•3 baths

•

~$80 less than other sites

Luxury Living: Grand near Everything

7 bedrooms•5 baths

•

~$75 less than other sites

317 N 4th Street

4 bedrooms•1.5 baths

•

New

~$65 less than other sites

All homes in St. Louis

5431 Pernod Avenue

5 bedrooms•2 baths

•

New

~$95 less than other sites

The Chase off Grand: Historic Shaw Home, Near Zoo & Arch

5 bedrooms•2 baths

•

~$40 less than other sites

6121 W Park Ave

4 bedrooms•2.5 baths

•

New

~$80 less than other sites

StayAtlas Retreat w/ Pool, Gym, Games, BBQ

7 bedrooms•6 baths

•

~$95 less than other sites

Lou Luxe- Speakeasy, EPIC Arcade, Hottub & FirePit

5 bedrooms•3 baths

•

~$80 less than other sites

Historic St Louis Retreat, Two Levels

6 bedrooms•4 baths

•

New

~$125 less than other sites

Luxury Living: Grand near Everything

7 bedrooms•5 baths

•

~$75 less than other sites

317 N 4th Street

4 bedrooms•1.5 baths

•

New

~$65 less than other sites

View all homes

Highlights in St. Louis

Gather your group to explore St. Louis’s iconic monuments, massive free parks, world-class zoo, and vibrant, interactive museum spaces.

Gateway Arch National Park

City Museum

Saint Louis Zoo

Busch Stadium

Anheuser-Busch Brewery

Missouri Botanical Garden

Forest Park

IT'S A VACATION HOME, BUT BETTER

The Wander difference

Wander is different because we combine the quality of a luxury hotel with the comfort of a private vacation home. Your best trip ever is just a few clicks away.

Only the best homes

We’ll never not look like the pictures. Every Wander is beautiful and expertly operated, so you can leave any stress at the door.

Hotel-grade amenities

We’ll never leave you with nothing to do. From ultra fast WiFi to gyms and pools, our homes make it easy to blend work and play.

24/7 concierge service

We’ll never leave you hanging. Our chat-based Concierge is always available to help – from trip questions to special requests.

Inspiring and stunning views

We’ll never leave you uninspired. Every Wander has stunning views to refresh and inspire your soul. Adventure awaits.

Meticulous cleaning

We’ll never have you check in to a dirty house. Our cleaning teams are meticulous, and there are no chores at checkout.

Safety and security

We’ll never pass you off to a stranger. Every Wander location meets our industry-leading safety standards to give you peace of mind.

Most popular amenities for large group vacation rentals in St. Louis

More popular large group destinations near St. Louis

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Discover more large groups activities in St. Louis

Midwestern warmth meets big-city culture in St. Louis, where the Mississippi frames a skyline crowned by the Gateway Arch. Days flow from riverfront views to leafy time in 1,300-acre Forest Park, and four distinct seasons bring spring blooms, summer festivals, crisp autumn color, and cozy winter lights.

The city shines for groups. Catch a Cardinals game at Busch Stadium, sing along on a blues night in Soulard, or wander the Delmar Loop and Grand Center’s theaters and galleries. Taste the city’s brewing heritage in historic brick breweries and buzzy taprooms. Centrally located and easy to reach via STL, St. Louis makes nationwide meetups simple. This is why Wander’s luxury large-group vacation rentals in St. Louis are the perfect choice, whether you are traveling for work or leisure.

FAQs: Vacation Rentals in St. Louis

Why should I book a Wander in St. Louis over other large group vacation rentals?

Wander offers a level of consistency and quality you won’t find with most large group vacation rentals.

Every home in St. Louis delivers the quality of a luxury hotel, paired with the comfort and space of a private vacation home. You get hotel-grade amenities, meticulous cleaning, stunning views, and 24/7 concierge support in every stay. Why would you want to stay anywhere else?

Which are Wander’s most popular large group vacation rentals in St. Louis?

Some of our most popular large group vacation rentals in St. Louis include 5431 Pernod Avenue, The Chase off Grand: Historic Shaw Home • Sleeps 14 • Near Zoo & Arch, and 6121 W Park Ave. Guests love the quality of a luxury hotel, the comfort of a private vacation home, and the consistently exceptional experience Wander is known for. Explore the full collection to find the perfect home for your next stay.

How many different large group vacation rentals does Wander have available in St. Louis?

Wander offers 8 large group vacation rentals in St. Louis, each carefully designed and expertly operated. Browse the full collection to see what’s available for your trip.

What time is check-in and check-out at Wander’s large group vacation rentals in St. Louis?

You can check-in to Wander large group vacation rentals in St. Louis after 4.00pm and check-out before 10.00am.

Do Wander’s large group vacation rentals in St. Louis have WiFi access?

Yes. Every Wander home in St. Louis has ultra fast, reliable WiFi so you can stay connected throughout your stay.

What is Wander’s cancellation policy?

You can cancel your reservation within 24 hours of booking for a full refund.

For stays of less than 15 nights, you can cancel or reschedule up to 14 days before check-in for a full refund. For stays of 15 nights or longer, the cancellation window is 60 days.

For some homes, a 30-day deadline applies; this will be clearly shown before you book.