Luxury Vacation Rentals for Families in Saint Louis

Never book a bad vacation home again. Every Wander comes with hotel-grade amenities, inspiring views, pristine cleaning and 24/7 concierge service.

We found 57 family vacation rentals – enter your dates for availability.

Top-rated family vacation rentals in Saint Louis

5431 Pernod Avenue

5 bedrooms•2 baths

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New

~$95 less than other sites

5403 Quincy Street Unit 1E

2 bedrooms•1 bath

•

New

~$30 less than other sites

2623 Ohio Ave

4 bedrooms•3.5 baths

•

New

~$90 less than other sites

3857 Blaine Ave

2 bedrooms•1 bath

•

New

~$45 less than other sites

5031 Chippewa Street

2 bedrooms•1 bath

•

New

~$30 less than other sites

6718 Dolan Place

2 bedrooms•1 bath

•

New

~$55 less than other sites

The Chase off Grand: Historic Shaw Home, Near Zoo & Arch

5 bedrooms•2 baths

•

~$40 less than other sites

StayAtlas Retreat w/ Pool, Gym, Games, BBQ

7 bedrooms•6 baths

•

~$95 less than other sites

Welcome to family adventures in Saint Louis

Discover the ease of traveling with kids at Wander’s luxury family vacation rentals in Saint Louis. Our homes pair hotel-grade consistency with the warmth of a private residence, so you can settle in quickly and enjoy every moment.

Expect multi-bedroom layouts, spacious living rooms for together time, and chef-ready kitchens. Thoughtfully designed indoor and outdoor areas encourage connection, while quiet work nooks keep parents productive. Every stay includes pristine cleaning, fast WiFi, and 24/7 concierge. With interiors that match the photos, your Saint Louis home base feels effortless and family-ready.

Available soon in Saint Louis

5431 Pernod Avenue

5 bedrooms•2 baths

•

New

~$95 less than other sites

5403 Quincy Street Unit 1E

2 bedrooms•1 bath

•

New

~$30 less than other sites

3857 Blaine Ave

2 bedrooms•1 bath

•

New

~$45 less than other sites

5031 Chippewa Street

2 bedrooms•1 bath

•

New

~$30 less than other sites

6718 Dolan Place

2 bedrooms•1 bath

•

New

~$55 less than other sites

StayAtlas Retreat w/ Pool, Gym, Games, BBQ

7 bedrooms•6 baths

•

~$95 less than other sites

Home in St. Louis

3 bedrooms•2.5 baths

•

New

~$70 less than other sites

Central CWE Luxury, King Beds, Huge Primary Suite

4 bedrooms•2 baths

•

~$60 less than other sites

All homes in Saint Louis

5431 Pernod Avenue

5 bedrooms•2 baths

•

New

~$95 less than other sites

5403 Quincy Street Unit 1E

2 bedrooms•1 bath

•

New

~$30 less than other sites

2623 Ohio Ave

4 bedrooms•3.5 baths

•

New

~$90 less than other sites

3857 Blaine Ave

2 bedrooms•1 bath

•

New

~$45 less than other sites

5031 Chippewa Street

2 bedrooms•1 bath

•

New

~$30 less than other sites

6718 Dolan Place

2 bedrooms•1 bath

•

New

~$55 less than other sites

The Chase off Grand: Historic Shaw Home, Near Zoo & Arch

5 bedrooms•2 baths

•

~$40 less than other sites

StayAtlas Retreat w/ Pool, Gym, Games, BBQ

7 bedrooms•6 baths

•

~$95 less than other sites

View all homes

Highlights in Saint Louis

Discover Saint Louis with family-friendly adventures, interactive museums, world-class parks, and iconic landmarks that create unforgettable memories for all ages.

Gateway Arch National Park

Saint Louis Zoo

City Museum

Saint Louis Science Center

Missouri Botanical Garden

Forest Park

The Magic House, St. Louis Children's Museum

IT'S A VACATION HOME, BUT BETTER

The Wander difference

Wander is different because we combine the quality of a luxury hotel with the comfort of a private vacation home. Your best trip ever is just a few clicks away.

Only the best homes

We’ll never not look like the pictures. Every Wander is beautiful and expertly operated, so you can leave any stress at the door.

Hotel-grade amenities

We’ll never leave you with nothing to do. From ultra fast WiFi to gyms and pools, our homes make it easy to blend work and play.

24/7 concierge service

We’ll never leave you hanging. Our chat-based Concierge is always available to help – from trip questions to special requests.

Inspiring and stunning views

We’ll never leave you uninspired. Every Wander has stunning views to refresh and inspire your soul. Adventure awaits.

Meticulous cleaning

We’ll never have you check in to a dirty house. Our cleaning teams are meticulous, and there are no chores at checkout.

Safety and security

We’ll never pass you off to a stranger. Every Wander location meets our industry-leading safety standards to give you peace of mind.

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Discover more family fun in Saint Louis

Saint Louis blends Midwestern friendliness with big-city culture and room to breathe. Forest Park anchors the city with miles of green and renowned attractions that spark curiosity for all ages. The City Museum inspires play, while the Saint Louis Zoo and Science Center turn learning into adventure.

From riverfront views at the Gateway Arch to ballgames that light up downtown, the city serves up memory-making moments in every season. Spring blooms at the Missouri Botanical Garden, vibrant fall color, and festive winter lights set the scene. Easy drive times and a central location simplify plans, which makes Wander’s luxury family vacation rentals in Saint Louis the perfect choice, whether you’re traveling for work or leisure.

FAQs: Vacation Rentals in Saint Louis

Why should I book a Wander in Saint Louis over other family vacation rentals?

Wander offers a level of consistency and quality you won’t find with most family vacation rentals.

Every home in Saint Louis delivers the quality of a luxury hotel, paired with the comfort and space of a private vacation home. You get hotel-grade amenities, meticulous cleaning, stunning views, and 24/7 concierge support in every stay. Why would you want to stay anywhere else?

Which are Wander’s most popular family vacation rentals in Saint Louis?

Some of our most popular family vacation rentals in Saint Louis include 5431 Pernod Avenue, 5403 Quincy Street Unit 1E, and 2623 Ohio Ave. Guests love the quality of a luxury hotel, the comfort of a private vacation home, and the consistently exceptional experience Wander is known for. Explore the full collection to find the perfect home for your next stay.

How many different family vacation rentals does Wander have available in Saint Louis?

Wander offers 57 family vacation rentals in Saint Louis, each carefully designed and expertly operated. Browse the full collection to see what’s available for your trip.

What time is check-in and check-out at Wander’s family vacation rentals in Saint Louis?

You can check-in to Wander family vacation rentals in Saint Louis after 4.00pm and check-out before 10.00am.

Do Wander’s family vacation rentals in Saint Louis have WiFi access?

Yes. Every Wander home in Saint Louis has ultra fast, reliable WiFi so you can stay connected throughout your stay.

What is Wander’s cancellation policy?

You can cancel your reservation within 24 hours of booking for a full refund.

For stays of less than 15 nights, you can cancel or reschedule up to 14 days before check-in for a full refund. For stays of 15 nights or longer, the cancellation window is 60 days.

For some homes, a 30-day deadline applies; this will be clearly shown before you book.