Luxury Vacation Rentals for Families in St. Louis

Never book a bad vacation home again. Every Wander comes with hotel-grade amenities, inspiring views, pristine cleaning and 24/7 concierge service.

We found 57 family vacation rentals – enter your dates for availability.

Top-rated family vacation rentals in St. Louis

5431 Pernod Avenue

5 bedrooms•2 baths

•

New

~$95 less than other sites

5403 Quincy Street Unit 1E

2 bedrooms•1 bath

•

New

~$30 less than other sites

2623 Ohio Ave

4 bedrooms•3.5 baths

•

New

~$90 less than other sites

3857 Blaine Ave

2 bedrooms•1 bath

•

New

~$45 less than other sites

5031 Chippewa Street

2 bedrooms•1 bath

•

New

~$30 less than other sites

6718 Dolan Place

2 bedrooms•1 bath

•

New

~$55 less than other sites

The Chase off Grand: Historic Shaw Home, Near Zoo & Arch

5 bedrooms•2 baths

StayAtlas Retreat w/ Pool, Gym, Games, BBQ

7 bedrooms•6 baths

•

~$95 less than other sites

Welcome to family adventures in St. Louis

Bring the whole crew together with Wander’s luxury family vacation rentals in St. Louis. Every home blends hotel-grade polish with the comfort of a private residence, so downtime feels as good as the day’s highlights.

Expect expansive living areas, multiple bedrooms for easy bedtime routines, and thoughtful layouts that keep connection and quiet in balance. You can count on ultra fast WiFi, pristine cleaning, inspiring views, and 24/7 concierge service, with select homes featuring private gyms or pools.

Book a space that makes family time effortless, from morning pancakes to movie night, and enjoy the confidence that it will look and feel exactly as promised.

Available soon in St. Louis

5431 Pernod Avenue

5 bedrooms•2 baths

•

New

~$95 less than other sites

5403 Quincy Street Unit 1E

2 bedrooms•1 bath

•

New

~$30 less than other sites

3857 Blaine Ave

2 bedrooms•1 bath

•

New

~$45 less than other sites

5031 Chippewa Street

2 bedrooms•1 bath

•

New

~$30 less than other sites

6718 Dolan Place

2 bedrooms•1 bath

•

New

~$55 less than other sites

StayAtlas Retreat w/ Pool, Gym, Games, BBQ

7 bedrooms•6 baths

•

~$95 less than other sites

Home in St. Louis

3 bedrooms•2.5 baths

•

New

~$70 less than other sites

Central CWE Luxury, King Beds, Huge Primary Suite

4 bedrooms•2 baths

•

~$60 less than other sites

All homes in St. Louis

5431 Pernod Avenue

5 bedrooms•2 baths

•

New

~$95 less than other sites

5403 Quincy Street Unit 1E

2 bedrooms•1 bath

•

New

~$30 less than other sites

2623 Ohio Ave

4 bedrooms•3.5 baths

•

New

~$90 less than other sites

3857 Blaine Ave

2 bedrooms•1 bath

•

New

~$45 less than other sites

5031 Chippewa Street

2 bedrooms•1 bath

•

New

~$30 less than other sites

6718 Dolan Place

2 bedrooms•1 bath

•

New

~$55 less than other sites

The Chase off Grand: Historic Shaw Home, Near Zoo & Arch

5 bedrooms•2 baths

StayAtlas Retreat w/ Pool, Gym, Games, BBQ

7 bedrooms•6 baths

•

~$95 less than other sites

View all homes

Highlights in St. Louis

Packed with world-class free attractions, interactive museums, and expansive parks, St. Louis offers unforgettable, action-packed adventures for families of all ages.

Saint Louis Zoo

City Museum

Gateway Arch

Saint Louis Science Center

The Magic House, St. Louis Children's Museum

Missouri Botanical Garden

IT'S A VACATION HOME, BUT BETTER

The Wander difference

Wander is different because we combine the quality of a luxury hotel with the comfort of a private vacation home. Your best trip ever is just a few clicks away.

Only the best homes

We’ll never not look like the pictures. Every Wander is beautiful and expertly operated, so you can leave any stress at the door.

Hotel-grade amenities

We’ll never leave you with nothing to do. From ultra fast WiFi to gyms and pools, our homes make it easy to blend work and play.

24/7 concierge service

We’ll never leave you hanging. Our chat-based Concierge is always available to help – from trip questions to special requests.

Inspiring and stunning views

We’ll never leave you uninspired. Every Wander has stunning views to refresh and inspire your soul. Adventure awaits.

Meticulous cleaning

We’ll never have you check in to a dirty house. Our cleaning teams are meticulous, and there are no chores at checkout.

Safety and security

We’ll never pass you off to a stranger. Every Wander location meets our industry-leading safety standards to give you peace of mind.

Most popular amenities for family vacation rentals in St. Louis

More popular family destinations near St. Louis

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Family vacation rentals in Springfield

Family vacation rentals in Deepwater

Family vacation rentals in Branson West

Family vacation rentals in Blue Eye

Other popular amenities & vacation types in St. Louis

Large group vacation rentals in St. Louis

Pet-friendly vacation rentals in St. Louis

Private pool vacation rentals in St. Louis

Discover more family fun in St. Louis

St. Louis makes family travel simple. The city pairs big-ticket icons like the Gateway Arch with an easygoing pace, short drives, and generous green space along the Mississippi.

Forest Park packs in days of discovery, from the free zoo to hands-on science, with trails and lakes in between. Kids of all ages love the imaginative climbs and slides at City Museum, while sports fans can catch the energy at Busch Stadium or Enterprise Center.

Season after season, you will find festivals, gardens in bloom, and riverfront views that make memories without the hassle. This is why Wander’s luxury family vacation rentals in St. Louis are the perfect choice, whether you are traveling for work or leisure.

FAQs: Vacation Rentals in St. Louis

Why should I book a Wander in St. Louis over other family vacation rentals?

Wander offers a level of consistency and quality you won’t find with most family vacation rentals.

Every home in St. Louis delivers the quality of a luxury hotel, paired with the comfort and space of a private vacation home. You get hotel-grade amenities, meticulous cleaning, stunning views, and 24/7 concierge support in every stay. Why would you want to stay anywhere else?

Which are Wander’s most popular family vacation rentals in St. Louis?

Some of our most popular family vacation rentals in St. Louis include 5431 Pernod Avenue, 5403 Quincy Street Unit 1E, and 2623 Ohio Ave. Guests love the quality of a luxury hotel, the comfort of a private vacation home, and the consistently exceptional experience Wander is known for. Explore the full collection to find the perfect home for your next stay.

How many different family vacation rentals does Wander have available in St. Louis?

Wander offers 57 family vacation rentals in St. Louis, each carefully designed and expertly operated. Browse the full collection to see what’s available for your trip.

What time is check-in and check-out at Wander’s family vacation rentals in St. Louis?

You can check-in to Wander family vacation rentals in St. Louis after 4.00pm and check-out before 10.00am.

Do Wander’s family vacation rentals in St. Louis have WiFi access?

Yes. Every Wander home in St. Louis has ultra fast, reliable WiFi so you can stay connected throughout your stay.

What is Wander’s cancellation policy?

You can cancel your reservation within 24 hours of booking for a full refund.

For stays of less than 15 nights, you can cancel or reschedule up to 14 days before check-in for a full refund. For stays of 15 nights or longer, the cancellation window is 60 days.

For some homes, a 30-day deadline applies; this will be clearly shown before you book.