Luxury Vacation Rentals for Families in Isle of Palms

Luxury Vacation Rentals for Families in Isle of Palms

Never book a bad vacation home again. Every Wander comes with hotel-grade amenities, inspiring views, pristine cleaning and 24/7 concierge service.
We found 77 family vacation rentals – enter your dates for availability.

Top-rated family vacation rentals in Isle of Palms

Oceanside Villas 211C - Villa Solea - 1400 Ocean Blvd Unit 211C property photo 1

Oceanside Villas 211C - Villa Solea - 1400 Ocean Blvd Unit 211C

2 bedrooms•2 baths
866 US dollars for 3 nights•

~$70 less than other sites

Palms Paradise - Home with Private Pool - 3 29th Ave property photo 1
Luxury

Palms Paradise - Home with Private Pool - 3 29th Ave

5 bedrooms•5.5 baths
3,195 US dollars for 3 nights•

~$280 less than other sites

Oceanside Villas 111C - Deja Blue - 1400 Ocean Blvd Unit 111C property photo 1

Oceanside Villas 111C - Deja Blue - 1400 Ocean Blvd Unit 111C

2 bedrooms•2 baths
981 US dollars for 3 nights•
New

~$80 less than other sites

Beach Please - 10 32nd Ave property photo 1
Luxury

Beach Please - 10 32nd Ave

5 bedrooms•4.5 baths
2,937 US dollars for 3 nights•

~$255 less than other sites

CM3302: 3302 Cameron Blvd property photo 1

CM3302: 3302 Cameron Blvd

6 bedrooms•5.5 baths
4,144 US dollars for 3 nights•
New

~$365 less than other sites

AV8-53: 8 53rd Avenue property photo 1

AV8-53: 8 53rd Avenue

5 bedrooms•3.5 baths
2,432 US dollars for 3 nights•
New

~$210 less than other sites

AV19-21: 19 21st Avenue property photo 1

AV19-21: 19 21st Avenue

6 bedrooms•5 baths
3,950 US dollars for 3 nights•
New

~$345 less than other sites

AV15-42: 15 42nd Avenue property photo 1

AV15-42: 15 42nd Avenue

6 bedrooms•6 baths
3,174 US dollars for 3 nights•
New

~$280 less than other sites

Welcome to family adventures in Isle of Palms

Welcome to family adventures in Isle of Palms

Make family time effortless with our luxury family vacation rentals in Isle of Palms. Wander pairs the consistency of a five-star hotel with the comfort of a private home, so everyone from toddlers to grandparents feels taken care of.
Choose expansive multi-bedroom layouts with bunk rooms, private pools, and sunlit great rooms that bring the whole crew together. Expect chef-ready kitchens, laundry rooms, ultra fast WiFi, and smart entertainment for movie nights. Many homes feature ocean-view decks and fenced outdoor spaces. Cribs, high chairs, and safety gear are available through our 24/7 concierge. Every stay includes pristine cleaning and hotel-grade amenities, all exactly as pictured.

Available soon in Isle of Palms

Oceanside Villas 211C - Villa Solea - 1400 Ocean Blvd Unit 211C property photo 1

Oceanside Villas 211C - Villa Solea - 1400 Ocean Blvd Unit 211C

2 bedrooms•2 baths
866 US dollars for 3 nights•

~$70 less than other sites

Oceanside Villas 111C - Deja Blue - 1400 Ocean Blvd Unit 111C property photo 1

Oceanside Villas 111C - Deja Blue - 1400 Ocean Blvd Unit 111C

2 bedrooms•2 baths
981 US dollars for 3 nights•
New

~$80 less than other sites

Beach Please - 10 32nd Ave property photo 1
Luxury

Beach Please - 10 32nd Ave

5 bedrooms•4.5 baths
2,937 US dollars for 3 nights•

~$255 less than other sites

CM3302: 3302 Cameron Blvd property photo 1

CM3302: 3302 Cameron Blvd

6 bedrooms•5.5 baths
4,144 US dollars for 3 nights•
New

~$365 less than other sites

AV19-21: 19 21st Avenue property photo 1

AV19-21: 19 21st Avenue

6 bedrooms•5 baths
3,950 US dollars for 3 nights•
New

~$345 less than other sites

AV15-42: 15 42nd Avenue property photo 1

AV15-42: 15 42nd Avenue

6 bedrooms•6 baths
3,174 US dollars for 3 nights•
New

~$280 less than other sites

AV4-22: 4 22nd Avenue property photo 1

AV4-22: 4 22nd Avenue

5 bedrooms•3.5 baths
2,626 US dollars for 3 nights•
New

~$230 less than other sites

Sea Glass - Home with Pool property photo 1

Sea Glass - Home with Pool

8 bedrooms•7 baths
4,044 US dollars for 3 nights•

~$360 less than other sites

Featured family vacation rentals in Isle of Palms

Twin Palms - Home with Pool property photo 1

Twin Palms - Home with Pool

7 bedrooms•5 baths
4,107 US dollars for 3 nights•

~$360 less than other sites

CM3008: 3008 Cameron Blvd property photo 1

CM3008: 3008 Cameron Blvd

7 bedrooms•7 baths
3,807 US dollars for 3 nights•
New

~$295 less than other sites

Beach Retreat - 3407 Palm Blvd property photo 1

Beach Retreat - 3407 Palm Blvd

9 bedrooms•9 baths
4,719 US dollars for 3 nights•

~$415 less than other sites

PALM2807: 2807 Palm Blvd property photo 1

PALM2807: 2807 Palm Blvd

7 bedrooms•7.5 baths
4,227 US dollars for 3 nights•
New

~$370 less than other sites

PALM3907: 3907 Palm Blvd property photo 1

PALM3907: 3907 Palm Blvd

8 bedrooms•8.5 baths
8,548 US dollars for 4 nights•
New

~$755 less than other sites

HN2307: 2307 Hartnett Blvd property photo 1

HN2307: 2307 Hartnett Blvd

5 bedrooms•4.5 baths
3,790 US dollars for 3 nights•
New

~$330 less than other sites

Shore Thing - 4001 Palm Blvd property photo 1
Luxury

Shore Thing - 4001 Palm Blvd

6 bedrooms•6.5 baths
6,779 US dollars for 4 nights•
New

~$600 less than other sites

Cameron By The Sea - 3203 Cameron Blvd property photo 1
Luxury

Cameron By The Sea - 3203 Cameron Blvd

6 bedrooms•7 baths
5,484 US dollars for 3 nights•

~$485 less than other sites

Highlights in Isle of Palms

Enjoy sun-soaked days on pristine beaches, gentle ocean waves, and a wealth of outdoor activities perfect for creating lasting family memories.
Isle of Palms County Park
Isle of Palms Marina
Front Beach
Wild Dunes Resort
Shem Creek Park
Patriots Point Naval & Maritime Museum
South Carolina Aquarium

IT'S A VACATION HOME, BUT BETTER

The Wander difference

Wander is different because we combine the quality of a luxury hotel with the comfort of a private vacation home. Your best trip ever is just a few clicks away.

Only the best homes

We’ll never not look like the pictures. Every Wander is beautiful and expertly operated, so you can leave any stress at the door.

Hotel-grade amenities

We’ll never leave you with nothing to do. From ultra fast WiFi to gyms and pools, our homes make it easy to blend work and play.

24/7 concierge service

We’ll never leave you hanging. Our chat-based Concierge is always available to help – from trip questions to special requests.

Inspiring and stunning views

We’ll never leave you uninspired. Every Wander has stunning views to refresh and inspire your soul. Adventure awaits.

Meticulous cleaning

We’ll never have you check in to a dirty house. Our cleaning teams are meticulous, and there are no chores at checkout.

Safety and security

We’ll never pass you off to a stranger. Every Wander location meets our industry-leading safety standards to give you peace of mind.

All homes in Isle of Palms

Oceanside Villas 211C - Villa Solea - 1400 Ocean Blvd Unit 211C property photo 1

Oceanside Villas 211C - Villa Solea - 1400 Ocean Blvd Unit 211C

2 bedrooms•2 baths
866 US dollars for 3 nights•

~$70 less than other sites

Palms Paradise - Home with Private Pool - 3 29th Ave property photo 1
Luxury

Palms Paradise - Home with Private Pool - 3 29th Ave

5 bedrooms•5.5 baths
3,195 US dollars for 3 nights•

~$280 less than other sites

Oceanside Villas 111C - Deja Blue - 1400 Ocean Blvd Unit 111C property photo 1

Oceanside Villas 111C - Deja Blue - 1400 Ocean Blvd Unit 111C

2 bedrooms•2 baths
981 US dollars for 3 nights•
New

~$80 less than other sites

Beach Please - 10 32nd Ave property photo 1
Luxury

Beach Please - 10 32nd Ave

5 bedrooms•4.5 baths
2,937 US dollars for 3 nights•

~$255 less than other sites

CM3302: 3302 Cameron Blvd property photo 1

CM3302: 3302 Cameron Blvd

6 bedrooms•5.5 baths
4,144 US dollars for 3 nights•
New

~$365 less than other sites

AV8-53: 8 53rd Avenue property photo 1

AV8-53: 8 53rd Avenue

5 bedrooms•3.5 baths
2,432 US dollars for 3 nights•
New

~$210 less than other sites

AV19-21: 19 21st Avenue property photo 1

AV19-21: 19 21st Avenue

6 bedrooms•5 baths
3,950 US dollars for 3 nights•
New

~$345 less than other sites

AV15-42: 15 42nd Avenue property photo 1

AV15-42: 15 42nd Avenue

6 bedrooms•6 baths
3,174 US dollars for 3 nights•
New

~$280 less than other sites

View all homes

Most popular amenities for family vacation rentals in Isle of Palms

Private chef (7)
Ev charger (3)
Outdoor pool (18)
Tennis court (23)
Jacuzzi (17)
Hot tub (17)
Sauna (1)
Ocean view (1)
Kayaks (14)
Heated pool (1)
Beach access (24)
Waterfront (2)
Patio (50)
Balcony (38)
Bicycle (1)
Garden (27)

More popular family destinations near Isle of Palms

Family vacation rentals in Mount Pleasant
Family vacation rentals in Sullivan's Island
Family vacation rentals in Charleston
Family vacation rentals in Folly Beach
Family vacation rentals in Murrells Inlet
Family vacation rentals in Garden City Beach
Family vacation rentals in Hilton Head Island

Other popular amenities & vacation types in Isle of Palms

Beachfront vacation rentals in Isle of Palms
Pet-friendly vacation rentals in Isle of Palms
Private pool vacation rentals in Isle of Palms
Large group vacation rentals in Isle of Palms
Hot tub vacation rentals in Isle of Palms
Discover more family fun in Isle of Palms

Discover more family fun in Isle of Palms

Seven miles of soft Atlantic shoreline set the pace on Isle of Palms, a barrier-island escape with gentle surf and wide, walkable sands. Mornings bring glowing sunrises, afternoons are for shelling and sandcastles, and golden hours stretch across the marsh.
Families appreciate the calm shallows, seasonal lifeguard zones, and easy beach access points. Nearby tidal creeks invite dolphin sightings and paddling, while bike-friendly roads keep adventures simple. All of this convenience and natural beauty is why Wander's luxury family vacation rentals in Isle of Palms are the perfect choice, whether you are traveling for work or leisure.

FAQs: Vacation Rentals in Isle of Palms

Why should I book a Wander in Isle of Palms over other family vacation rentals?

Wander offers a level of consistency and quality you won’t find with most family vacation rentals.
Every home in Isle of Palms delivers the quality of a luxury hotel, paired with the comfort and space of a private vacation home. You get hotel-grade amenities, meticulous cleaning, stunning views, and 24/7 concierge support in every stay. Why would you want to stay anywhere else?

Which are Wander’s most popular family vacation rentals in Isle of Palms?

Some of our most popular family vacation rentals in Isle of Palms include Oceanside Villas 211C - Villa Solea - 1400 Ocean Blvd Unit 211C, Palms Paradise - 5 BR Home with Private Pool - 3 29th Ave, and Oceanside Villas 111C - Deja Blue - 1400 Ocean Blvd Unit 111C. Guests love the quality of a luxury hotel, the comfort of a private vacation home, and the consistently exceptional experience Wander is known for. Explore the full collection to find the perfect home for your next stay.

How many different family vacation rentals does Wander have available in Isle of Palms?

Wander offers 77 family vacation rentals in Isle of Palms, each carefully designed and expertly operated. Browse the full collection to see what’s available for your trip.

What time is check-in and check-out at Wander’s family vacation rentals in Isle of Palms?

You can check-in to Wander family vacation rentals in Isle of Palms after 4.00pm and check-out before 10.00am.

Do Wander’s family vacation rentals in Isle of Palms have WiFi access?

Yes. Every Wander home in Isle of Palms has ultra fast, reliable WiFi so you can stay connected throughout your stay.

What is Wander’s cancellation policy?

You can cancel your reservation within 24 hours of booking for a full refund.
For stays of less than 15 nights, you can cancel or reschedule up to 14 days before check-in for a full refund. For stays of 15 nights or longer, the cancellation window is 60 days.
For some homes, a 30-day deadline applies; this will be clearly shown before you book.